Dr. Noaiseh is the site principal investigator for several randomized clinical trials assessing efficacy of different novel biological therapies in the management of Sjögren’s Syndrome and Systemic Lupus Erythematosus.

His interest is in studying how the overlap of autoimmune rheumatic diseases affects the clinical phenotype, disease course and response to therapy; specifically, the overlap of Sjögren’s Syndrome with other autoimmune diseases such as Systemic Lupus Erythematosus, myositis and Scoleroderma.

UPMC Sjogren’s Registry was established in 2014. The purpose is to collect data and blood samples of patients with Sjogren’s syndrome to facilitate research and collaboration with other institutions in this field.